Maté is spearheading the use of complex in vitro and in vivo models for studying the cell-intrinsic actin cytoskeleton cues and dynamics that govern the invasive migration of tumour cells, the tissue scanning of T cells and their cytotoxic interaction with tumour cells. Using a multidisciplinary approach encompassing cell biology, biophysics, bioimage informatics and advanced light microscopy, he aims to unravel fundamental actin-based processes and develop new methodologies for basic cell biological research. Maté’s research relies heavily on advanced microscopy and the development of image analysis platforms capable of automatically detecting and analysing the kinetics of actomyosin, cell movement and protrusions.

- Source, EMBL Australia